EF-Tu-targeting toxin
2022. Salmonella antibacterial Rhs polymorphic toxin inhibits translation through ADP-ribosylation of EF-Tu P-loop. Nucleic Acids Res. 50, 13114-13127.
PMID: 36484105
Bacillus T7SS YukC
2022. The antibacterial type VII secretion system of Baciluus subtilis: structure and interactions of the pseudokinase YukC/EssB. mBio. 13, e0013422.
PMID: 36154281
T9SS cryo-ET
Song L., Perpich J.D., Wu C.G., Doan T., Nowakowska Z., Potempa J. Christie P.J., Cascales E., Lamont R. Hu B. 2022. A unique bacterial secretion machinery with multiple secretion centers. Proc Natl Acad Sci USA. 119, e2119907119.
PMID: 35471908
This study and the work on the GldLM molecular motor have been featured on the CNRS website (in French): le T9SS, une mitrailleuse à 8 canons !
GldLM Motor
Vincent M.S., Comas Hervada C., Sebban-Kreuzer C., Le Guenno H., Chabalier M., Kosta A., Guerlesquin F., Mignot T., McBride M.J., Cascales E., Doan T. 2022. Dynamic proton-dependent motors power type IX secretion and gliding motility in Flavobacterium. PLOS Biology. in press
PMID: 35333857
T9SS JDR Review
Veith P.D., Glew M.D., Gorasia D.G., Cascales E., Reynolds E.C. 2022. The T9SS system and its role in bacterial function and pathogenesis. J Dent Res. 101, 374-383.
PMID: 34889148
PorW-Sov interaction
Gorasia D.G., Lunar Silva I., Butler C.A., Chabalier M., Doan T., Cascales E., Veith P.D., Reynolds E.C. 2022. Protein interactome analysis of the type IX secretion system identifies PorW as the missing link between the PorK/N ring complex and the Sov translocon. Microbiol. Spectrum. 10, e0160221.
PMID: 35019767
PorN structure
Fuchsbauer O., Lunar Silva I., Cascales E., Roussel A., Leone P. 2022. Structural and functional analyses of the Porphyromonas gingivalis type IX secretion system PorN protein. J Biol Chem. 298, 101618.
PMID: 35065963
TiM Spotlight
Jurenas D., Cascales E. 2022. T6SS: killing two bugs with one stone. Trends Microbiol. 30, 1-2.
Commentary on Le et al. Proc Natl Acad Sci USA. 118, e2106555118.
PMID: 34753653
