Welcome to Mélanie, who joined us as Engineer. She obtained her PhD from the University of Amsterdam (Laboratory of Joen Luirink), working on the insertion of bacterial membrane proteins.
Recent news from the lab
Yassine presented a poster on his work on the T6SS baseplate at the 13thannual Salk Fondation/ Ipsen science symposium on biological complexity.
Yoann’s article on TagA was awarded “Article of the month” from the Société Française de Biochimie et Biologie Moléculaire (French Society for Biochemistry and Molecular Biology).
TagA helps T6SS to hold their fire. Our work makes the cover of the Nature Microbiology November 2018 issue.
The work of the lab has been highlighted in the Mathieu Vidard’s chronicle (l’édito carré) at the France Inter radio broadcast “Game of Thrones chez les bactéries” !!
Yoann gave a presentation of his work at the ETMM2018 and received the award for the best talk. Congrats !!
Laure, Thierry, Maialène, Maxence, Ignacio, Yassine, Yoann and Eric C. participated to the Thematic School of Molecular Microbiology (Carry-le-Rouet, France).
Ignacio and Eric C. presented the work on T9SS and T6SS at the EMBO & FEMS “Bacterial Protein Export” meeting in Leuven (Belgium).
The identification of the T6SS latch is featured on the CNRS webpage.
Maxence and Yoann participated to the 84th Harden conference on single-molecule bacteriology (Oxford, UK).
Eric D. participated to the ESCMID Conference on Drug Development (Lisbon, Portugal).
Thank you the ANR for funding two of our projects on Type VI secretion effectors and membrane complex ! Congratulations Laure and Eric D. !!
Welcome to Etienne who joined the lab as engineer for 3 years !
Congratulations to Maxence who was awarded a Fondation pour la Recherche Médicale 4th year fellowship to pursue his work on T9SS ! Thank you the FRM for supporting us !
Ignacio and Yassine gave talks to present their works at the JSM3 meeting. Maxence and Yoann presented a poster. Yoann was awarded the best poster presentation, and Yassine the best “striptease” (no video for Yassine striptease, sorry !!). The award picture also features Pierre from Stéphane Canaan’s lab, who won the best oral presentation.
The team has been awarded the “Equipe 2018” label from the Fondation pour la Recherche Médicale. Thank you to all the generous funders ! Please make a donation to the FRM !
Happy to host Giuseppina Mariano from the Sarah Coulthurst‘s lab ! Great work to identify new players for T6SS effector activation !
Happy to host Dukas Jurenas from the laboratory of Laurence van Melderen (Brussels, Belgium) ! Great work on toxin-antitoxin systems !
Ryan Ellison, an undergraduate student from Exeter College of Oxford University was awarded a Laidlaw scholarship to develop a summer project in our lab ! Congrats Ryan !!
Eric C. gave a seminar at the Max Planck Institute for terrestrial biology in Marburg (Germany).
Eric C. gave a lecture on “Guerres Intestines” at the Collège de France (Paris).
Eric C. gave a plenary lecture at the Japanese IGER International symposium on cell surfaces (Nagoya).
Eric C. gave the 9th Joel Mandelstam lecture at the University of Oxford (UK).
Happy to host a new post-doc in the lab ! Welcome Victoria. And thank you the generous funders of Espoir contre la Mucoviscidose for funding Victoria’s work ! Please make donation to the association !
Eric C. gave a plenary lecture at the Belgium Society for Microbiology.
We are happy to have Maïalène and Thierry joining the lab !
Thank you the ANR for funding our new project (T6-PLATFORM) on the assembly of the Type VI secretion system !
It is out !!! Laure and Eric C. edited the Methods in Molecular Biology book on “Bacterial protein secretion systems” that includes 36 method chapters to study secretion systems (and other multiprotein machines) !
The work on the TssK structure and its role in docking the baseplate to the membrane complex is featured on the CNRS website.
Congratulations to Yoann who obtained a fellowship to continue his work as a Ph.D student !
Eric C. gave a conference at the Annual UK Microbiology Society (Edinburgh, Scotland, UK)
The lab participated to a popularization article on the T6SS for a french magazine for kids “Science et Vie Junior” !
Laure and Eric C. represented the lab at the Zing Conference on Protein Transport and Translocation (Tampa, USA).
Rahim is awarded the best 2015 thesis from the Aix-Marseille Université !
Well done !!
Congratulations to Yassine who obtained a Ph.D fellowship to join the group !
Rahim received the Dina Surdin Award from the French Society for Biochemistry and Molecular Biology (SFBBM).
from the group of Annabelle Merieau at the University of Evreux / Rouen.
Laureen obtained a 4th year Ph.D fellowship from the Fondation pour la Recherche Médicale !
Rahim received the Bettencourt-Schueller Award for his Ph.D work ! Congrats again !!
Rahim was selected for a présentation at the “Académie des Sciences” (French National Academy of Science) as one of the six major progresses in France in 2015 ! Congrats
Our work on the T6SS tail assembly regulation by TssA is featured on the CNRS website.
Rahim and Eric celebrate their TssA paper in Nature ! Champagne !
Nicolas describes the poison he identified at the extremity of the spike, at the Huffington Post: ma thèse en deux minutes.
Rahim has an article in the newspaper “Var matin” !
Congrats Eric D. for the ESCMID research grant !
Maxence left for a 5-week stay in Margaret Duncan’s laboratory (Forsyth Institute, Boston, USA).
Congratulations to Rahim for the SFBBM (French Society for Biochemistry and Molecular Biology) award of the best article of the month (for the TssJLM membrane complex Nature paper) !
Press release : our work on the T6SS is featured in Arte Future.
Our work on the TssJLM membrane complex is featured on the CNRS website.
Our work on the TssJLM membrane complex is featured in Nature Reviews in Microbiology.
Laureen Logger presents a short talk at the ‘Bacteria and Phage Meeting’ (Madison, USA)
Marie-Stéphanie hired as Faculty Member at the University of Brest !
Best wishes ! Proud of our Alumni !
We are now on Twitter ! #CascalesLab
Our paper on the assembly and structure of the T6SS membrane complex is now online on the Nature website !
Congratulations to Maxence for his Master 2 diploma and the thesis fellowship !
Congratulation to Laureen for her Award of the ‘Best Oral Presentation’ at the Doctoral School meeting !
Eric C. is presenting the ‘Assembly and structure of the T6SS membrane complex’ at the FEMS meeting in Maastricht (The Netherlands).
Congratulation to Rahim for his ‘Nature Reviews in Microbiology’ Award of the Best Poster Presentation at the BacNet15 meeting !
Rahim is presenting a poster at the BacNet 2015 meeting at San Feliu de Guixol (Spain).
Laure, Rahim, Laureen, Nicolas and Maxence are at the Institut Pasteur Symposium on ‘Bacterial Membranes’.
Eric C. is giving a talk at the EMBO Conference on ‘Mechanism and Regulation of Protein translocation’ in Dubrovnik (Croatia).
Rahim was awarded the Jean-Pierre Ebel Award of the SFBBM – a travel grant to participate to a conference. Let’s go to the BacNet15 meeting !
We are happy to host Sarah Tjaden, a visiting Ph.D student from the group of Ulrich Dobrindt at the University of Muenster (Germany) until July
Maxence joined the lab for his Master 2 training work. He will focus his work on the characterization of a T9SS subunit.
Rahim is leaving the lab for a 4-week training period in Remi Fronzes’s laboratory (Pasteur Institute, Paris).
Laure, Laureen and Rahim are at the “Ecole thématique de Microbiologie” in Carry-le-Rouet (France).
Eric C. gave a plenary lecture at the latin-american PGPR meeting in Cordoba (Argentina).
Nicolas succeeded at his Master 2 ! Congratulations !
Laure and Rahim are at the Gordon Conference on ‘Bacterial Cell Surfaces’ (Vermont, USA).
Thank you to our three undergraduate trainees, Doriane, Alexandre and Yoann, for the time and efforts in the lab !
Elodie obtained the best mark for her oral presentation on the work she has done in the lab with Laure ! Not for her performance in Bowling !
Laure and Laureen are at the 3d Molecular Microbiology meeting in Würzburg (Germany).
Nicolas joined the lab for his Master 2 training period. He will work with Laure on the effectors delivered by the T6SS in enteroaggregative E. coli.