Santin Y.G., Camy C.E., Zoued A., Doan T., Aschtgen M.S., Cascales E.. 2019. Role and recruitment of the TagL peptidoglycan-binding protein during Type VI secretion system biogenesis. J. Bacteriol. 201, e00173-19

PMID: 30910811

see more >

Cryo-EM TssJLM

Rapisarda C., Cherrak Y., Kooger R., Schmidt V., Pellarin R., Logger L., Cascales E., Pilhofer M., Durand E., Fronzes R. 2019. In situ and high-resolution cryo-EM structure of a bacterial Type VI secretion system membrane complex. EMBO J. 38, e100886

PMID: 30877094

see more >

T6SS baseplate wedge

Cherrak Y., Rapisarda C., Pellarin R., Bouvier G., Bardiaux B., Allain F. Malosse C., Rey M., Chamot-Rooke J., Cascales E., Fronzes R., Durand E. 2018. Biogenesis and structure of a Type VI secretion baseplate. Nat. Microbiol. 3, 1404-1416 .

PMID: 30323254

see more >

see the Behind the paper  “Building the blocks of a bacterial weapon” by Chiara.


Santin Y.G., Doan T., Lebrun R., Espinosa L., Journet L., Cascales E. 2018. In vivo proximity labelling during Type VI secretion biogenesis reveals TagA as a protein that stops and holds the sheath. Nat. Microbiol. 3, 1304-1313 .

PMID: 30275513

see more >

see the Behind the paper  “The Type VI secretion system under tension” by Yoann.

see the CNRS press release here

see the News and Views “Tagging the Type VI secretion system” by Olivera Francetic.


Renault M.G., Zamarreno Beas J., Douzi B., Chabalier M. Zoued A., Brunet Y.R., Cambillau C., Journet L., Cascales E. 2018. The gp27-like hub of VgrG serves as adaptor to promote Hcp tube assembly. J. Mol. Biol. 430, 3143-3156.

PMID: 30031895

see more >


Zoued A., Duneau J.P., Durand E., Espana A.P., Journet L., Guerlesquin F., Cascales E. 2018. Tryptophan-mediated dimerization of the TssL transmembrane anchor is required for Type VI secretion system activity. J. Mol. Biol. 430, 987-1003.

PMID: 29458124

see more >