MuF

Bartoli J, Tempier AC, Guzzi NL, Piras CM, Cascales E, Viala JPM. 2023. Characterization of a (p)ppApp synthetase belonging to a new family of polymorphic toxin associated with temperate phages. J Mol Biol. 435, 168282.

PMID: 37730083

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PAAR

Beauvois SG, Flaugnatti N, Ilbert M, Boyer M, Gavello-Fernandez E, Fronzes R, Jurenas D, Journet L. 2023. The tip protein PAAR is required for the function of the type VI secretion system. Microbiol Spectr. 6, e0147823.

PMID: 37800964

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MFE01 amidase

Bourigault Y, Dupont CA, Desjardins JB, Doan T, Bouteiller M, Le Guenno H, Chevalier S, Barbey C, Latour X, Cascales E, Merieau A. 2023. Pseudomonas fluorescens MFE01 delivers a putative type VI secretion amidase that confers biocontrol against the soft-rot pathogen Pectobacterium atrosepticum. Environ Microbiol. 25, 2564-2579.

PMID: 37622480

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LAGA and SAGK methods

Taillefer B, Grandjean M, Herrou J, Robert D,  Mignot T, Sebban-Kreuzer C, Cascales E. 2023. Qualitative and quantitative methods to measure antibacterial activity resulting from bacterial competition. Bio-Protocol. 13, e4706.

PMID: 37449039

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AIEC T6SS Tle3 phospholipase

Le TTH, Kellenberger C, Boyer M, Santucci P, Flaugnatti N, Cascales E, Roussel A, Canaan S, Journet L, Cambillau C. 2023. Activity and crystal structure of the adherent-invasive Escherichia coli Tle3/Tli3 T6SS effector/immunity complex determined using an AlphaFold2 predicted model. Int J Mol Sci. 24, 1740.

PMID: 36675258

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EF-Tu-targeting toxin

Jurenas D, Rey M, Byrne D, Chamot-Rooke J, Terradot L, Cascales E.. 2022. Salmonella antibacterial Rhs polymorphic toxin inhibits translation through ADP-ribosylation of EF-Tu P-loop. Nucleic Acids Res. 50, 13114-13127.

PMID: 36484105

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Bacillus T7SS YukC

Tassinari M, Doan T, Bellinzoni M, Chabalier M, Ben-Assaya M, Martinez M, Gaday Q, Alzari PM, Cascales E, Fronzes R, Gubellini F. 2022. The antibacterial type VII secretion system of Baciluus subtilis: structure and interactions of the pseudokinase YukC/EssB. mBio. 13, e0013422.

PMID: 36154281

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T9SS cryo-ET

Song L., Perpich J.D., Wu C.G., Doan T., Nowakowska Z., Potempa J. Christie P.J., Cascales E., Lamont R. Hu B. 2022. A unique bacterial secretion machinery with multiple secretion centers. Proc Natl Acad Sci USA. 119, e2119907119.

PMID: 35471908

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This study and the work on the GldLM molecular motor have been featured on the CNRS website (in French): le T9SS, une mitrailleuse à 8 canons !