LAGA and SAGK methods

Taillefer B, Grandjean M, Herrou J, Robert D,  Mignot T, Sebban-Kreuzer C, Cascales E. 2023. Qualitative and quantitative methods to measure antibacterial activity resulting from bacterial competition. Bio-Protocol. 13, e4706.

PMID: 37449039

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AIEC T6SS Tle3 phospholipase

Le TTH, Kellenberger C, Boyer M, Santucci P, Flaugnatti N, Cascales E, Roussel A, Canaan S, Journet L, Cambillau C. 2023. Activity and crystal structure of the adherent-invasive Escherichia coli Tle3/Tli3 T6SS effector/immunity complex determined using an AlphaFold2 predicted model. Int J Mol Sci. 24, 1740.

PMID: 36675258

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EF-Tu-targeting toxin

Jurenas D, Rey M, Byrne D, Chamot-Rooke J, Terradot L, Cascales E.. 2022. Salmonella antibacterial Rhs polymorphic toxin inhibits translation through ADP-ribosylation of EF-Tu P-loop. Nucleic Acids Res. 50, 13114-13127.

PMID: 36484105

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Bacillus T7SS YukC

Tassinari M, Doan T, Bellinzoni M, Chabalier M, Ben-Assaya M, Martinez M, Gaday Q, Alzari PM, Cascales E, Fronzes R, Gubellini F. 2022. The antibacterial type VII secretion system of Baciluus subtilis: structure and interactions of the pseudokinase YukC/EssB. mBio. 13, e0013422.

PMID: 36154281

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T9SS cryo-ET

Song L., Perpich J.D., Wu C.G., Doan T., Nowakowska Z., Potempa J. Christie P.J., Cascales E., Lamont R. Hu B. 2022. A unique bacterial secretion machinery with multiple secretion centers. Proc Natl Acad Sci USA. 119, e2119907119.

PMID: 35471908

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This study and the work on the GldLM molecular motor have been featured on the CNRS website (in French): le T9SS, une mitrailleuse à 8 canons !

GldLM Motor

Vincent M.S., Comas Hervada C., Sebban-Kreuzer C., Le Guenno H., Chabalier M., Kosta A., Guerlesquin F., Mignot T., McBride M.J., Cascales E., Doan T. 2022. Dynamic proton-dependent motors power type IX secretion and gliding motility in Flavobacterium. PLOS Biology. in press

PMID: 35333857

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PorW-Sov interaction

Gorasia D.G., Lunar Silva I., Butler C.A., Chabalier M., Doan T., Cascales E., Veith P.D., Reynolds E.C. 2022. Protein interactome analysis of the type IX secretion system identifies PorW as the missing link between the PorK/N ring complex and the Sov translocon. Microbiol. Spectrum. 10, e0160221.

PMID: 35019767

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